AirHint found the following cheapest one-way flights from Lisbon (LIS) to Prague (PRG) in December 2025 (see full year).

One-Way flights

18 Dec	easyJet	direct
16 Dec	easyJet	direct
20 Dec	easyJet	direct
23 Dec	easyJet	direct
13 Dec	easyJet	direct
27 Dec	easyJet	direct
04 Dec	easyJet	direct
11 Dec	easyJet	direct
02 Dec	easyJet	direct
09 Dec	easyJet	direct

Also check the deals for return flights from Lisbon to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Lisbon to Prague in December from 36€

One-Way flights