AirHint found the following cheapest one-way flights from Lisbon (LIS) to Prague (PRG) in December 2025 (see full year).
One-Way flights
| 23 Dec | easyJet | direct | |
| 22 Dec | Ryanair | ||
| 24 Dec | Iberia | ||
| 20 Dec | Ryanair | ||
| 28 Dec | easyJet | ||
| 25 Dec | Air Serbia | ||
| 26 Dec | Vueling Airlines | ||
| 21 Dec | Air Europa | ||
| 20 Dec | easyJet | direct | |
| 27 Dec | easyJet | direct |
Also check the deals for return flights from Lisbon to Prague in December.
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