AirHint found the following cheapest one-way flights from Lisbon (LIS) to Istanbul (IST) in December 2025 (see full year).

One-Way flights

01 Dec	Vueling Airlines
12 Dec	SKY express
07 Dec	SKY express
14 Dec	SKY express
10 Dec	Wizz Air
30 Dec	Vueling Airlines
31 Dec	Aegean Airlines
21 Dec	Aegean Airlines
24 Dec	Aegean Airlines
16 Dec	Ryanair

Also check the deals for return flights from Lisbon to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Lisbon to Istanbul in December from 79€

One-Way flights