Cheapest one-way flights from Los Angeles to Santiago in September from 369€

Best time to book flights for Los Angeles (LAX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

05 Sep LATAM Airlines Group
01 Sep Delta direct
05 Sep Delta direct

Also check the deals for return flights from Los Angeles to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago