Cheapest one-way flights from Los Angeles to Santiago in December from 286€

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

07 Dec Spirit Airlines
10 Dec LATAM Airlines Group
08 Dec LATAM Airlines Group
09 Dec LATAM Airlines Group
11 Dec LATAM Airlines Group
02 Dec LATAM Airlines Group
06 Dec LATAM Airlines Group
08 Dec Delta direct
09 Dec Delta direct
02 Dec LATAM Airlines Group direct

Also check the deals for return flights from Los Angeles to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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