AirHint found the following cheapest one-way flights from New York (JFK) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

09 Dec	Avianca
07 Dec	Avianca
11 Dec	Avianca
15 Dec	Avianca
09 Dec	LATAM Airlines Group	direct
10 Dec	Delta	direct
11 Dec	Delta	direct
24 Dec	Delta
25 Dec	LATAM Airlines Group
23 Dec	LATAM Airlines Group

Also check the deals for return flights from New York to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from New York to Santiago in December from 287€

One-Way flights