Cheapest one-way flights from New York to Santiago in December from $224

AirHint found the following cheapest one-way flights from New York (JFK) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

05 Dec Frontier Airlines
04 Dec Frontier Airlines
03 Dec Frontier Airlines
08 Dec Frontier Airlines
09 Dec Frontier Airlines
15 Dec Frontier Airlines
29 Dec Frontier Airlines
09 Dec LATAM Airlines Group direct
15 Dec LATAM Airlines Group direct
28 Dec LATAM Airlines Group

Also check the deals for return flights from New York to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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