AirHint found the following cheapest one-way flights from Istanbul (IST) to Prague (PRG) in December 2025 (see full year).

One-Way flights

22 Dec	Pegasus Airlines	direct
09 Dec	Pegasus Airlines	direct
23 Dec	Pegasus Airlines	direct
15 Dec	Pegasus Airlines	direct
08 Dec	Pegasus Airlines	direct
06 Dec	Pegasus Airlines	direct
27 Dec	Pegasus Airlines	direct
13 Dec	Pegasus Airlines	direct
11 Dec	Pegasus Airlines	direct
03 Dec	Pegasus Airlines

Also check the deals for return flights from Istanbul to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Istanbul to Prague in December from 54€

One-Way flights