Cheapest one-way flights from Houston to Santiago in December from 190€

AirHint found the following cheapest one-way flights from Houston (IAH) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

08 Dec Frontier Airlines
10 Dec Spirit Airlines
27 Dec Frontier Airlines
25 Dec Spirit Airlines
15 Dec Spirit Airlines
26 Dec Spirit Airlines
26 Dec United direct
27 Dec United direct
08 Dec United direct
10 Dec United direct

Also check the deals for return flights from Houston to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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