Cheapest one-way flights from Houston to Santiago in April from 311€

Best time to book flights for Houston (HOU) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Houston (HOU) to Santiago (SCL) in April 2025 (see full year).

One-Way flights

05 Apr Aeromexico
04 Apr Avianca

Also check the deals for return flights from Houston to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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