Cheapest one-way flights from Houston to Santiago in November from 429CAD

AirHint found the following cheapest one-way flights from Houston (HOU) to Santiago (SCL) in November 2025 (see full year).

One-Way flights

15 Nov Spirit Airlines
15 Nov United direct

Also check the deals for return flights from Houston to Santiago in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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