AirHint found the following cheapest one-way flights from Houston (HOU) to Sao Paulo (GRU) in December 2025 (see full year).
One-Way flights
| 03 Dec | Spirit Airlines | ||
| 23 Dec | Frontier Airlines | ||
| 26 Dec | GOL Linhas Aéreas | ||
| 23 Dec | United | direct | |
| 03 Dec | United | direct | |
| 26 Dec | United | direct | |
| 22 Dec | United | direct | |
| 16 Dec | United | direct |
Also check the deals for return flights from Houston to Sao Paulo in December.
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