AirHint found the following cheapest one-way flights from Sao Paulo (GRU) to Milano (MXP) in December 2025 (see full year).

One-Way flights

01 Dec	Iberia
02 Dec	Iberia
05 Dec	LATAM Airlines Group	direct
01 Dec	LATAM Airlines Group	direct
02 Dec	LATAM Airlines Group	direct
10 Dec	LATAM Airlines Group	direct
04 Dec	Iberia
11 Dec	LATAM Airlines Group
04 Dec	LATAM Airlines Group	direct
12 Dec	LATAM Airlines Group	direct

Also check the deals for return flights from Sao Paulo to Milano in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Sao Paulo to Milano in December from 324€

One-Way flights