AirHint found the following cheapest one-way flights from Florence (FLR) to Brussels (BRU) in September 2025 (see full year).

One-Way flights

25 Sep	Vueling Airlines	direct
18 Sep	Vueling Airlines	direct
16 Sep	Vueling Airlines	direct
06 Sep	Vueling Airlines	direct
09 Sep	Vueling Airlines	direct
02 Sep	Vueling Airlines	direct
11 Sep	Vueling Airlines	direct
10 Sep	Volotea
03 Sep	Vueling Airlines
01 Sep	Volotea

Also check the deals for return flights from Florence to Brussels in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Florence to Brussels in September from 27€

One-Way flights