AirHint found the following cheapest one-way flights from Rome (FCO) to Lisbon (LIS) in September 2025 (see full year).

One-Way flights

30 Sep	Wizz Air Malta
23 Sep	Ryanair
24 Sep	Wizz Air Malta
27 Sep	Wizz Air Malta	direct
28 Sep	Wizz Air Malta
26 Sep	Wizz Air Malta
25 Sep	Ryanair
20 Sep	Wizz Air Malta
30 Sep	Ryanair	direct
23 Sep	Wizz Air Malta	direct

Also check the deals for return flights from Rome to Lisbon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Rome to Lisbon in September from 77€

One-Way flights