AirHint found the following cheapest one-way flights from Rome (FCO) to Sao Paulo (GRU) in April 2026 (see full year).

One-Way flights

13 Apr	Wizz Air Malta
23 Apr	Ryanair
14 Apr	Iberia
16 Apr	Ryanair
08 Apr	Vueling Airlines
29 Apr	Ryanair
02 Apr	LATAM Airlines Group	direct
03 Apr	LATAM Airlines Group	direct
16 Apr	LATAM Airlines Group	direct
01 Apr	ITA Airways

Also check the deals for return flights from Rome to Sao Paulo in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Rome to Sao Paulo in April from 322€

One-Way flights