AirHint found the following cheapest one-way flights from Amsterdam (AMS) to Prague (PRG) in December 2025 (see full year).

One-Way flights

01 Dec	easyJet	direct
06 Dec	easyJet	direct
29 Dec	easyJet	direct
09 Dec	easyJet	direct
03 Dec	easyJet	direct
16 Dec	easyJet	direct
30 Dec	easyJet	direct
04 Dec	easyJet	direct
08 Dec	easyJet	direct
25 Dec	easyJet	direct

Also check the deals for return flights from Amsterdam to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Amsterdam to Prague in December from 68€

One-Way flights